Address: 27 Welbeck Street, London, W1G 8EN
Tel: 020 7101 3377


Liver Disease: Types of Liver Problems, Causes, and More

Liver disease encompasses a range of conditions affecting the liver, an organ crucial for digesting food, removing toxins from the body, and regulating metabolism. Liver diseases can be caused by various factors, including genetics, infections, excessive alcohol consumption, and obesity, leading to inflammation, scarring (cirrhosis), or liver failure. Early detection and management are key to preventing serious complications.

Types of Liver Disease

  • Hepatitis: Inflammation of the liver, often caused by viruses (hepatitis A, B, C, D, and E), excessive alcohol use, or autoimmune diseases.
  • Fatty Liver Disease: Accumulation of fat in liver cells, which can be non-alcoholic fatty liver disease (NAFLD) or alcoholic liver disease (ALD).
  • Cirrhosis: Late-stage liver disease characterized by scarring of the liver and impaired liver function, often resulting from chronic hepatitis or chronic alcoholism.
  • Liver Cancer: Primary liver cancer originates in the liver, with hepatocellular carcinoma being the most common type. Liver cancer can also result from metastasis of cancers from other organs.
  • Autoimmune Liver Diseases: Conditions where the immune system attacks the liver, including autoimmune hepatitis, primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC).
  • Genetic Liver Diseases: Hereditary conditions affecting the liver, such as hemochromatosis (iron buildup in the body) and Wilson’s disease (copper accumulation in the liver).

Symptoms of Liver Disease

Symptoms may not be apparent in the early stages but can include:

  • Jaundice (yellowing of the skin and eyes)
  • Abdominal pain and swelling
  • Swelling in the legs and ankles
  • Itchy skin
  • Dark urine color
  • Pale stool color
  • Chronic fatigue
  • Nausea or vomiting
  • Loss of appetite
  • Tendency to bruise easily


Diagnosing liver disease involves a combination of medical history, physical examination, and specific tests:

  • Blood Tests: Liver function tests to assess levels of liver enzymes, proteins, and bilirubin.
  • Imaging Tests: Ultrasound, CT scans, and MRI to visualize the liver’s structure and identify abnormalities.
  • Liver Biopsy: Removing a tissue sample from the liver for examination under a microscope.
  • Non-invasive Tests: FibroScan (transient elastography) to measure liver stiffness and assess fibrosis or cirrhosis.


Treatment varies based on the type and stage of liver disease:

  • Lifestyle Changes: Reducing alcohol consumption, eating a healthy diet, and exercising can help manage certain liver diseases, especially NAFLD and ALD.
  • Medications: To treat hepatitis or autoimmune liver diseases.
  • Surgery: Liver transplant may be considered for patients with end-stage liver disease or liver cancer.
  • Managing Complications: Treatment may also focus on managing complications of liver disease, such as bleeding disorders, ascites, and encephalopathy.


Preventive measures can significantly reduce the risk of developing liver disease:

  • Vaccination against hepatitis A and B.
  • Practicing safe sex and avoiding needle sharing.
  • Limiting alcohol consumption and maintaining a healthy weight.
  • Avoiding exposure to environmental toxins.

Regular check-ups and monitoring are important for individuals at risk of liver disease, allowing for early detection and management. If you suspect you have symptoms of liver disease, seek medical evaluation promptly to determine the cause and appropriate treatment.

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Address: 27 Welbeck Street, London, W1G 8EN

Telephone020 7101 3377